Coeliac/Gluten Profile 2
*To reduce the risk of missing IgA deficient patients, a Total IgA will be run for all low Tissue Transglutaminase IgA results. If IgA deficiency is identified, a reflex deaminated Gliadin IgG will be carried out to determine whether the patient is likely to have coeliac disease. Coeliac pathway:
- Initial TTG IgA samples are received and tested
- If TTG IgA is LOW <0.2 U/ml reflex testing for Total IgA will be undertaken
- If Total IgA is LOW <0.1 g/L then reflex testing for Gliadin IgG test will be undertaken
- If TTG IgA is HIGH (>/= 10 U/ml then reflex testing for Endomesial IgA will be undertaken as a confirmatory test.
Sample type guide