Coeliac/Gluten Profile 2
Gliadin deamidated lgG
Tissue Transglutaminase (IgA)
*To reduce the risk of missing IgA deficient patients, a Total IgA will be run for all low Tissue Transglutaminase IgA results. If IgA deficiency is identified, a reflex deaminated Gliadin IgG will be carried out to determine whether the patient is likely to have coeliac disease. Coeliac pathway:
- Initial TTG IgA samples are received and tested
- If TTG IgA is LOW <0.2 U/ml reflex testing for Total IgA will be undertaken
- If Total IgA is LOW <0.1 g/L then reflex testing for Gliadin IgG test will be undertaken
- If TTG IgA is HIGH (>/= 10 U/ml then reflex testing for Endomesial IgA will be undertaken as a confirmatory test.
Sample type guide
Lavender Vacutainer, EDTA anticoagulant, 4ml/10ml (10ml EDTA tubes are used for specific PCR assays)
Gold Vacutainer, SST/Gel anticoagulant, 5ml
See the Sample Requirements page for an explanation of all the sample requirements.
See the Special Instructions Legend page for a full list of special instructions.