Sample Reqs

AB

Turnaround

10 days

Special instructions

If IgA deficiency is identified, a reflex deamidated Gliadin IgG will be carried out to determine whether the patient is likely to have coeliac disease.

Coeliac pathway:

1. Initial TTG IgA samples are received and tested
2. If TTG IgA is LOW <0.2 U/ml reflex testing for Total IgA will be undertaken
3. If Total IgA is LOW <0.1 g/L then reflex testing for deamidated Gliadin IgG test will be undertaken
4. If TTG IgA is HIGH (>/= 10 U/ml) or in the equivocal range (7–10 U/ml) then reflex testing for Endomysial IgA will be undertaken as a confirmatory test for first time positive samples.