Category

Skin and Soft Tissue

Code

3SK

To prevent tissue degeneration, it is advisable to collect histopathology samples in sample pot(s) containing preservative, usually formalin, to at least ten times the volume of the tissue sample (available from TDL Supplies). Use of preservative will ensure that the tissue architecture and microscopic appearances of specimens are preserved.

Patient demographics, together with clinical and sample details need to be provided with the specimens. Testicular investigations for reproductive investigations are best submitted fixed in Bouins solution. Requests for products of conception require the patient’s signed consent/instruction regarding sensitive disposal when the histopathology is complete. Please contact 020 7307 7380 or 020 7307 7373 for information or any query relating to histopathology.

All specimens are initially stained with H&E. However special stains and immunohistochemistry (IHC) may be recommended if additional information is needed to provide a more detailed analysis. The choice of stain depends on the findings on initial assessment, the clinical context and the preference of the pathologist within their specialist expertise. IHC may be added when routine or regular histological testing is not sufficient to form a diagnosis.